The Genomics and Bioinformatics Group now forms part of the Germans Trias i Pujol Research Institute (IGTP) within the Program for Predictive and Personalized Medicine of Cancer.

Please see the IGTP website here

This page is being kept up to date, but for information about the institute, please see the IGTP page.

The main goal of the Genomics Laboratory at the IMPPC will be to provide the institution with state of the art genomics and bioinformatics technologies to give support to the activities of its researchers. We envision the gradual implementation of platforms complemented by outsourcing and contracting of external services, emphasizing the building of a team of experts in experimental design and sample preparation, and in bioinformatic data analysis. We aim to develop new methods for the discovery and typing of novel molecular markers for cancer and other disease prediction, centering on the use of DNA polymorphisms (SNPs and CNVs), differential gene expression (specifically of miRNAs and other non-coding RNAs), and chromatin modifications (DNA methylation), and the generation of predictors based on genomic data that can have an application on cancer preventive medicine.

Our Research

Available Resources

Main emphasis will be in covering technological areas related to the study of nucleic acids with high throughput / high information content approaches, including the use of DNA chips or microarrays, genotyping assays, quantitative PCR based quantitation methods, and conventional, second and third generation DNA sequencing.

Group Members:

Previous Members of Lab:


CRG, University of Barcelona, IDIBELL, CREAL, Hospital Trias i Pujol, IR Vall d'Hebron 


  • Use of miRNA Expression Profiles in Serum for the Study of Cancer Progression

    Investigador principalFinançadorsData d'iniciData de finalització
    Lauro Sumoy ISCIII01-01-201131-12-2013


Lauro Sumoy
(+34) 93 554 3075
Office 0-9 (ground floor)

Genomics and Bioinformatics

Publicacions rellevants

Rech G, Vilaplana C, Velasco J, Pluvinet R, Santín S, Prat C, Julián E, Alcaide F, Comas I, Sumoy L, Cardona PJ. Draft Genome Sequences of Mycobacterium setense Type Strain DSM-45070 and the Nonpathogenic Strain Manresensis, Isolated from the Bank of the Cardener River in Manresa, Catalonia, Spain. Genome Announc 2015 Feb; 3(1)

Llorens F, Hummel M, Pantano L, Pastor X, Vivancos A, Castillo E, Mattlin H, Ferrer A, Ingham M, Noguera M, Kofler R, Dohm JC, Pluvinet R, Bayés M, Himmelbauer H, del Río JA, Martí E, Sumoy L. Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor. BMC Genomics 2013 Jun; 14: 371

Llorens F, Hummel M, Pastor X, Ferrer A, Pluvinet R, Vivancos A, Castillo E, Iraola S, Mosquera AM, González E, Lozano J, Ingham M, Dohm JC, Noguera M, Kofler R, del Río JA, Bayés M, Himmelbauer H, Sumoy L. Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis. BMC Genomics 2011 Jun; 12: 326

Martí E, Pantano L, Bañez-Coronel M, Llorens F, Miñones-Moyano E, Porta S, Sumoy L, Ferrer I, Estivill X. A myriad of miRNA variants in control and Huntington's disease brain regions detected by massively parallel sequencing. Nucleic Acids Res. 2010 Nov; 38(20): 7219-35

Pluvinet R, Olivar R, Krupinski J, Herrero-Fresneda I, Luque A, Torras J, Cruzado JM, Grinyó JM, Sumoy L, Aran JM. CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling. Blood 2008 Nov; 112(9): 3624-37

Puigdecanet E, Espinet B, Lozano JJ, Sumoy L, Bellosillo B, Arenillas L, Alvarez-Larrán A, Solé F, Serrano S, Besses C, Florensa L. Gene expression profiling distinguishes JAK2V617F-negative from JAK2V617F-positive patients in essential thrombocythemia. Leukemia 2008 Jul; 22(7): 1368-76

Llorens F, Gil V, Iraola S, Carim-Todd L, Martí E, Estivill X, Soriano E, del Río JA, Sumoy L. Developmental analysis of Lingo-1/Lern1 protein expression in the mouse brain: interaction of its intracellular domain with Myt1l. Dev Neurobiol 2008 Mar; 68(4): 521-41

Mengual L, Burset M, Ars E, Ribal MJ, Lozano JJ, Minana B, Sumoy L, Alcaraz A. Partially degraded RNA from bladder washing is a suitable sample for studying gene expression profiles in bladder cancer. Eur. Urol. 2006 Dec; 50(6): 1347-55; discussion 1355-6

Veure-les totes

Generalitat de Catalunya

Unió Europea


Universitat Autònoma de Barcelona

Ajuntament de Badalona

Institut Català de la Salut

Germans Trias i Pujol Hospital

Fundació Institut d'investigació en Ciències de la Salut Germans Trias i Pujol

Back to Top