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27-28 March 2014

V Annual IMPPC Conference:

Integrative and Computational Biology Joint symposium V IMPPC Annual Conference and 4DCellFate Workshop

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The fifth annual IMPPC Conference on Integrative and Computational was a joint venture: V IMPPC Annual Conference and 4DCellFate Workshop. It took place on 27 and 28 March in the auditorium at the Barcelona Biomedical Research Park (PRBB) in Barcelona.

The conference was organized by Tanya Vavouri of the IMPPC, Ana Rojas, formerly of the IMPPC and now of the Institute of Biomedicine Seville (IBIS) and Ben Lehner of the 4DCellFate Project of the CRG.

The conference covered topics in genomics, cancer evolution, chromatin and epigenetics. The speakers included international researchers, leaders in these fields, who showcased how computational analyses of big biological datasets can offer novel biological insights. Chromatin and cancer genomics were central topics of many of the talks. Among the chromatin topics discussed were modeling of DNA molecules, nucleosomes and large chromosomal domains and studying how DNA methylation, small RNAs and transcription factors regulate genes both during normal development and in disease. Large cancer genome datasets and their mutation patterns are used as tools to predict oncogenes and tumor suppressors and also to study how cancers evolve and even construct the history of a transmissible tumour in dogs and tasmanian devils.

Highlights of the conference were two sessions of fast-track presentations where young researchers summarized in a concise and a highly effective way the main point of their work. Speakers, poster presenters and the audience interacted at coffee and lunch breaks in front of the posters, despite the unexpectedly chilly March wind.

The first day of the conference ended with the EMBO Keynote Lecture by Søren Brunak who gave a masterful overview of the national registry of Danish electronic patient records and how it is being used to study disease trajectories and uncover interactions between diseases, environment and drugs giving us a glimpse of studies that may become possible in many other countries in the future.


Generalitat de Catalunya

Unió Europea


Universitat Autònoma de Barcelona

Ajuntament de Badalona

Institut Català de la Salut

Germans Trias i Pujol Hospital

Fundació Institut d'investigació en Ciències de la Salut Germans Trias i Pujol