Barcelona 8-10 April 2015


Program

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Wednesday 8 April

16:00-16:10

Opening of the Conference

Welcome Remarks by Manuel Perucho, Director IMPPC
Introduction by organizers: Jun Yokota

16:10-17:50

Session 1: Target Cancer Genes (1)Chair: Manuel Perucho

16:10-16:50

Mariano Barbacid

Spanish National Cancer Research Center (CNIO), Spain
Targeting Cancer Genes: The K-Ras signaling pathway in lung and pancreatic tumors

16:50-17:20

Laura Soucek

Vall d'Hebron Institute of Oncology (VHIO), Spain
Preclinical validation of Myc inhibition by a new generation of Omomyc-peptides

17:20-17:50

Montse Sanchez-Céspedes

Bellvitge Biomedical Research Institute (IDIBELL), Spain
Dissection of the BRG1 and MYC/MAX biological connection and its use in lung cancer therapeutics

17:50-18:20

Coffee break

18:20-20:00

Session 2: Genome-wide StudiesChair: Agustí Barnadas

18:20-18:30

Agustí Barnadas

(Hospital Sant Pau) Barcelona, Spain
Introduction to Hospital Sant Pau

18:30-19:00

Jun Yokota

Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Spain
MYC inhibition as a therapeutic strategy in small cell lung cancer

19:00-19:30

Martin Sos

University of Cologne, Germany
Targeting molecular dependencies in cancer

19:30-19:45

Short Talk: Roberto Mosca

(IRB) Barcelona, Spain
dSysMap: exploring the edgetic role of disease mutations

19:45-20:00

Short Talk: Santi Gonzalez

(BSC) Barcelona, Spain
Characterisation of complex rearrangements in cancer genomes

Thursday 9 April

09:00-10:40

Session 3: Prediction Markers (1)Chair: Laura Soucek

09:00-09:40

Allan Balmain

University of California, San Francisco (UCSF), USA
Integration of germline and somatic genetic events during tumor evolution

09:40-10:10

Eduard Serra

Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Spain
Genomics of Peripheral Nerve Sheath Tumors in Neurofibromatosis

10:10-10:40

Fast Track Presentations of Posters Session 1

10:40-11:00

Coffee break

11:00-13:00

Session 4: Target Cancer Genes (2)Chair: Montse Sánchez-Céspedes

11:00-11:40

Kristiina Vuori

Sanford-Burnham Medical Research Institute (SBMRI), La Jolla, USA
Identification of Novel Cancer Targets in Glioblastoma

11:40-12:20

Curtis C. Harris

National Cancer Institute (NCI), Maryland, USA
Interweaving the threads of p53, microRNA, DNA methylation and inflammation networks into the tapestry of cancer and aging

12:20-13:00

Fast Track Talks for Poster Presenters 2

13:00-15:30

Lunch and Poster Session

14:30-16:00

Session 5: Prediction Markers (2)Chair: Eduard Serra

14:30-14:45

Short Talk: Silvestre Vicent

(CIMA) Pamplona, Spain 
An integrative cross-species, cross-tumors gene-expression approach unveils novel
oncogene dependencies in mutant KRAS tumors

14:45-15:00

Short Talk: Johanna Samuelsson

(Active Motif Inc.) San Diego, USA
Transposase-Assisted Chromatin immunoprecipitation (TAM-ChIP) as a tool for the simultaneous investigation of multiple targets in FFPE cancer tissues

15:00-15:30

Pedro Medina

Genyo, Centre for Genomics and Oncological Research, Spain
MicroRNAs, Chromatin Remodeling complexes and cancer

15:30-16:00

Eduard Eyras

Universitat Pompeu Fabra (UPF) and ICREA, Spain
RNA processing alterations as drivers and prognostic markers of cancer

16:00-16:30

Coffee break

16:30-17:40

Chair: Curtis C.Harris

16:30-17:10

Carlo Croce

University of Ohio, USA
Causes and consequences of microRNA dysregulation in cancer

17:10-17.40

Egbert Smit

VU University, Amsterdam, Netherlands
Molecular imaging using radiolabeled drugs in lung cancer

17:40-18:40

Cocktail and Poster Session

Friday 10 April

9:00-10:30

Session 6: Drug DiscoveryChair: Rafael Rosell

09:00-09:30

Aleix Prat

Department of Clinical Oncology, Hospital Clínic, Spain
Clinical Implications of the Intrinsic Molecular Subtypes of Breast Cancer

09:30-10:00

Matthew Holderfield

Frederick National Laboratory for Cancer Research, USA
Targeting KRAS on multiple fronts: drug discovery efforts at Frederic National Laboratory for Cancer Research
 

10:00-10:30

Robert Torka

Max-Planck Institute of Biochemistry, Munich, Germany
Compensatory mechanisms to AXL Receptor Tyrosine Kinase Inhibitors

10:30-11:00

Coffee break

11:00-13:00

Sesson 7: Target TherapyChair: Jun Yokota

11:00-11:40

Takashi Kohno

National Cancer Center Research Institute (NCCRI), Tokyo, Japan
RET fusion and chromatin remodeling genes: targets for precision lung cancer medicine

11:40-12:20

Rafael Rosell

The Catalan Institute of Oncology (ICO), Spain
Bypass tracks in lung cancer resistance

12:20-13:00

Webster Cavenee

University of California, San Diego (UCSD) - La Jolla; USA
A novel “hide and seek” mechanism driving therapeutic resistance

13:00

Closing Remarks

Rafael Rosell

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