III IMPPC Annual Conference:

Barcelona, 3-4 May 2012



The organizers reserve the right to make changes to this program if circumstances require.

The titles given her are orientative, please consult this page for program updates.

Thursday 3 May



Opening of conference and Welcome remarks
Introduction by Juan Valcárcel, Director RNAREG Consortium
Introduction by Manuel Perucho, Director IMPPC


Session I: Regulation of Post Transcriptional Control of Gene Expression: an overviewChair: Mayka Sanchez (IMPPC, RNAREG)

Adrian Krainer, Cold Spring Harbor Laboratory (CSHL), (USA)
SRSF1: A Splicing Factor Oncoprotein

Matthias W. Hentze, The European Molecular Biology Laboratory (EMBL), (Germany)
Translational control by RNA-binding proteins- title to be confirmed

Mayka Sanchez, IMPPC, RNAREG (Spain)
Iron regulatory proteins and iron-response elements: new frontiers



12.10- 14.15

Session II: RNA Splicing, Processing, Quality control and decay: Mechanism and diseasesChair: Raul Mendez (RNAREG)

Tom Cooper, Baylor College of Medicine, Houston (USA)
Alternative splicing regulatory networks in development and disease

Javier Cáceres, Programme Leader of RNA Processing in Eukaryotes. Medical Research Council (MRC, Edinburgh)
Regulation of microRNA biogenesi and Function

Andreas Kulozik, Kinderklinik University Heidelberg, (Germany)
Regulated 3' end mRNA processing in disease


Short talk I


Lunch and poster session

15.30 -17.20

Session III: Short non-coding RNAs in cancer and diseasesChair: Lauro Sumoy (IMPPC)

Carlo Croce, Human Cancer Genetics Program, Ohio State University (USA)
Contribution of miRNAs to human malignancies - title to be confirmed

Reuven Agami, The Netherlands Cancer Institute, Amsterdam (The Netherlands)
Genomic analysis of alternative poly-adenylation in human cells

Gunter Meister, Department of Biochemistry I, Faculty of Biology and Preclinical Medicine, University of Regensburg (Germany)
The role of miRNAs in glioblastoma



17.50 - 19.20

Session IV: Circulating and exosomal miRNAs and cancerChair: Fatima Gebauer (RNAREG)

Lauro Sumoy, IMPPC
Next generation sequencing analysis of miRNA isomir heterogeneity in serum

CY Zhang
Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, Nanjing University

19.05 - 19.20

Short talk II

19.20 - 20.00

Cocktail and posters

Friday 4 May


Session V: Long non-coding RNAs in cancer and diseasesChair: Maite Huarte (RNAREG)

John Rinn, Department of Pathology, Beth Israel and Deaconess Medial Center and the Department of Stem Cell and Regenerative Biology, Harvard Medical School and The Broad Institute of Harvard and MIT (USA)
Large non-coding RNAs in development and disease - title to be confirmed

Denise Barlow, CeMM Research Center for Molecular Medicine of the Austrian Academy of Science Austria)
Imprinted genes are silenced by unspliced macro IncRNAs

Manel Esteller , Programa de Epigenética y Biología del Cáncer (PEBC) del Instituto de Investigaciones Biomedicas de Bellvitge (IDIBELL). Barcelona (Spain)
Epigenetic and Genetic Disruption of Non-Coding RNAs in Human Disease




Session VI: RNA TherapeuticsChair: Marisol Soengas (RNAREG)

Luigi Naldini, San Raffaele Telethon Institute for Gene Therapy (Italy)
miRNA regulation in gene therapy title to be confirmed

Susanna Obad, MicroRNA Research at Santaris Pharma (Denmark)
Targeting of microRNAs for therapeutics


Short Talk III


Short Talk IV


Closing Remarks